null

SMILES: N[C@H]1CCC(CC1)Nc1ncc(\C=C\c2ccc(NS(=O)(=O)c3ccccc3Cl)nn2)cn1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM661994 (N-(6-((E)-2-(2-(((1r,4r)-4- aminocyclohexyl)amino)...) Show SMILES N[C@H]1CCC(CC1)Nc1ncc(\C=C\c2ccc(NS(=O)(=O)c3ccccc3Cl)nn2)cn1 |r,wD:1.0,(11.34,-.77,;10,-1.54,;8.67,-.77,;7.34,-1.54,;7.34,-3.08,;8.67,-3.85,;10,-3.08,;6,-3.85,;4.67,-3.08,;3.33,-3.85,;2,-3.08,;2,-1.54,;.67,-.77,;-.67,-1.54,;-2,-.77,;-2,.77,;-3.33,1.54,;-4.67,.77,;-6,1.54,;-7.34,.77,;-8.11,-.56,;-6.57,-.56,;-8.67,1.54,;-10,.77,;-11.34,1.54,;-11.34,3.08,;-10,3.85,;-8.67,3.08,;-7.34,3.85,;-4.67,-.77,;-3.33,-1.54,;3.33,-.77,;4.67,-1.54,)| Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human))	BDBM661994 (N-(6-((E)-2-(2-(((1r,4r)-4- aminocyclohexyl)amino)...) Show SMILES N[C@H]1CCC(CC1)Nc1ncc(\C=C\c2ccc(NS(=O)(=O)c3ccccc3Cl)nn2)cn1 |r,wD:1.0,(11.34,-.77,;10,-1.54,;8.67,-.77,;7.34,-1.54,;7.34,-3.08,;8.67,-3.85,;10,-3.08,;6,-3.85,;4.67,-3.08,;3.33,-3.85,;2,-3.08,;2,-1.54,;.67,-.77,;-.67,-1.54,;-2,-.77,;-2,.77,;-3.33,1.54,;-4.67,.77,;-6,1.54,;-7.34,.77,;-8.11,-.56,;-6.57,-.56,;-8.67,1.54,;-10,.77,;-11.34,1.54,;-11.34,3.08,;-10,3.85,;-8.67,3.08,;-7.34,3.85,;-4.67,-.77,;-3.33,-1.54,;3.33,-.77,;4.67,-1.54,)| Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair