BDBM50154614 CHEMBL187926::N-(4-cinnamoylphenyl)acetamide::N-[4-(3-Phenyl-acryloyl)-phenyl]-acetamide::WR-080539

SMILES: CC(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccccc1

InChI Key: InChIKey=CUYJTAUCYGHYLW-KPKJPENVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MO15-related protein kinase Pfmrk (Plasmodium falciparum)	BDBM50154614 (CHEMBL187926 | N-(4-cinnamoylphenyl)acetamide | N-...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C17H15NO2/c1-13(19)18-16-10-8-15(9-11-16)17(20)12-7-14-5-3-2-4-6-14/h2-12H,1H3,(H,18,19)/b12-7+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Walter Reed Army Institute of Research Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum cyclin-dependent kinase				J Med Chem 47: 5418-26 (2004) Article DOI: 10.1021/jm040108f BindingDB Entry DOI: 10.7270/Q2BZ66TW
					More data for this Ligand-Target Pair
MO15-related protein kinase Pfmrk (Plasmodium falciparum)	BDBM50154614 (CHEMBL187926 | N-(4-cinnamoylphenyl)acetamide | N-...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C17H15NO2/c1-13(19)18-16-10-8-15(9-11-16)17(20)12-7-14-5-3-2-4-6-14/h2-12H,1H3,(H,18,19)/b12-7+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation counting				Bioorg Med Chem Lett 19: 1982-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.042 BindingDB Entry DOI: 10.7270/Q2P26Z1T
					More data for this Ligand-Target Pair