BDBM50193022 (E)-1-(4-methoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one::1-(4-methoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one::CHEMBL221741::WR-289017

SMILES: COc1ccc(cc1)C(=O)\C=C\c1cccc2ccccc12

InChI Key: InChIKey=QUCMFZOJKRASJO-SDNWHVSQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase Pfmrk (Plasmodium falciparum)	BDBM50193022 ((E)-1-(4-methoxyphenyl)-3-(naphthalen-1-yl)prop-2-...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1cccc2ccccc12 Show InChI InChI=1S/C20H16O2/c1-22-18-12-9-17(10-13-18)20(21)14-11-16-7-4-6-15-5-2-3-8-19(15)16/h2-14H,1H3/b14-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation counting				Bioorg Med Chem Lett 19: 1982-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.042 BindingDB Entry DOI: 10.7270/Q2P26Z1T
					More data for this Ligand-Target Pair