BDBM50526156 CHEMBL1630208::WR301861

SMILES: Nc1cccc(c1)-c1csc(NC(=O)CCCCCC(=O)NO)n1

InChI Key: InChIKey=MYNZGQDLFHVZAO-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50526156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 2 (Homo sapiens (Human))	BDBM50526156 (CHEMBL1630208 | WR301861) Show SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCCC(=O)NO)n1 Show InChI InChI=1S/C16H20N4O3S/c17-12-6-4-5-11(9-12)13-10-24-16(18-13)19-14(21)7-2-1-3-8-15(22)20-23/h4-6,9-10,23H,1-3,7-8,17H2,(H,20,22)(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assay				Eur J Med Chem 166: 369-380 (2019) Article DOI: 10.1016/j.ejmech.2019.01.077
					More data for this Ligand-Target Pair
Histone deacetylase 10 (Homo sapiens (Human))	BDBM50526156 (CHEMBL1630208 | WR301861) Show SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCCC(=O)NO)n1 Show InChI InChI=1S/C16H20N4O3S/c17-12-6-4-5-11(9-12)13-10-24-16(18-13)19-14(21)7-2-1-3-8-15(22)20-23/h4-6,9-10,23H,1-3,7-8,17H2,(H,20,22)(H,18,19,21)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HDAC10 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assay				Eur J Med Chem 166: 369-380 (2019) Article DOI: 10.1016/j.ejmech.2019.01.077
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50526156 (CHEMBL1630208 | WR301861) Show SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCCC(=O)NO)n1 Show InChI InChI=1S/C16H20N4O3S/c17-12-6-4-5-11(9-12)13-10-24-16(18-13)19-14(21)7-2-1-3-8-15(22)20-23/h4-6,9-10,23H,1-3,7-8,17H2,(H,20,22)(H,18,19,21)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assay				Eur J Med Chem 166: 369-380 (2019) Article DOI: 10.1016/j.ejmech.2019.01.077
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50526156 (CHEMBL1630208 | WR301861) Show SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCCC(=O)NO)n1 Show InChI InChI=1S/C16H20N4O3S/c17-12-6-4-5-11(9-12)13-10-24-16(18-13)19-14(21)7-2-1-3-8-15(22)20-23/h4-6,9-10,23H,1-3,7-8,17H2,(H,20,22)(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assay				Eur J Med Chem 166: 369-380 (2019) Article DOI: 10.1016/j.ejmech.2019.01.077
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50526156 (CHEMBL1630208 | WR301861) Show SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCCC(=O)NO)n1 Show InChI InChI=1S/C16H20N4O3S/c17-12-6-4-5-11(9-12)13-10-24-16(18-13)19-14(21)7-2-1-3-8-15(22)20-23/h4-6,9-10,23H,1-3,7-8,17H2,(H,20,22)(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assay				Eur J Med Chem 166: 369-380 (2019) Article DOI: 10.1016/j.ejmech.2019.01.077
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50526156 (CHEMBL1630208 | WR301861) Show SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCCC(=O)NO)n1 Show InChI InChI=1S/C16H20N4O3S/c17-12-6-4-5-11(9-12)13-10-24-16(18-13)19-14(21)7-2-1-3-8-15(22)20-23/h4-6,9-10,23H,1-3,7-8,17H2,(H,20,22)(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assay				Eur J Med Chem 166: 369-380 (2019) Article DOI: 10.1016/j.ejmech.2019.01.077
					More data for this Ligand-Target Pair