BDBM50042982 2',3,4-trihydroxychalcone::3-(3,4-Dihydroxy-phenyl)-1-(2-hydroxy-phenyl)-propenone::CHEMBL339587::cid_5709318

SMILES: Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1O

InChI Key: InChIKey=PSYVAIWGYVDYHN-FNORWQNLSA-N

Data: 3 IC50  1 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50042982   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RecName: Full=Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM50042982 (2',3,4-trihydroxychalcone | 3-(3,4-Dihydroxy-pheny...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1O Show InChI InChI=1S/C15H12O4/c16-12-4-2-1-3-11(12)13(17)7-5-10-6-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-5+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.23E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2D798VP
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POsterior Segregation family member (pos-1) (Caenorhabditis elegans)	BDBM50042982 (2',3,4-trihydroxychalcone | 3-(3,4-Dihydroxy-pheny...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1O Show InChI InChI=1S/C15H12O4/c16-12-4-2-1-3-11(12)13(17)7-5-10-6-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-5+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28G8J4C
					More data for this Ligand-Target Pair
large T antigen (Simian virus 40)	BDBM50042982 (2',3,4-trihydroxychalcone | 3-(3,4-Dihydroxy-pheny...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1O Show InChI InChI=1S/C15H12O4/c16-12-4-2-1-3-11(12)13(17)7-5-10-6-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a
Southern Research Specialized Biocontainment Screening Center Curated by PubChem BioAssay					Assay Description Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2ZK5F47
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Myocilin (Homo sapiens)	BDBM50042982 (2',3,4-trihydroxychalcone | 3-(3,4-Dihydroxy-pheny...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1O Show InChI InChI=1S/C15H12O4/c16-12-4-2-1-3-11(12)13(17)7-5-10-6-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-5+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a
Center for the Study of Systems Biology, School of Biology, Georgia Institute of Technology, 950, Atlantic Drive, Atlanta, GA 30332, United States. Curated by ChEMBL					Assay Description Binding affinity myocilin-OLF domain (unknown origin) by Sypro Orange dye-based DSF assay				Bioorg Med Chem Lett 27: 4133-4139 (2017) Article DOI: 10.1016/j.bmcl.2017.07.035 BindingDB Entry DOI: 10.7270/Q2NG4T4K
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Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042982 (2',3,4-trihydroxychalcone | 3-(3,4-Dihydroxy-pheny...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1O Show InChI InChI=1S/C15H12O4/c16-12-4-2-1-3-11(12)13(17)7-5-10-6-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 5-lipoxygenase in rat RBL1 cells				Citation and Details Article DOI: 10.1007/s00044-013-0745-7 BindingDB Entry DOI: 10.7270/Q22N53QB
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Cyclooxygenase (Homo sapiens (Human))	BDBM50042982 (2',3,4-trihydroxychalcone | 3-(3,4-Dihydroxy-pheny...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1O Show InChI InChI=1S/C15H12O4/c16-12-4-2-1-3-11(12)13(17)7-5-10-6-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-5+	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description Inhibition of Prostaglandin G/H synthase activity in sheep seminal vesicle was determined 100 uM				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042982 (2',3,4-trihydroxychalcone | 3-(3,4-Dihydroxy-pheny...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2O)cc1O Show InChI InChI=1S/C15H12O4/c16-12-4-2-1-3-11(12)13(17)7-5-10-6-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair