BDBM50311887 6-bromo-N-(3-chlorophenyl)quinazolin-4-amine::CHEMBL1079374::cid_720635

SMILES: Clc1cccc(Nc2ncnc3ccc(Br)cc23)c1

InChI Key: InChIKey=LYKXFKUSOXETGV-UHFFFAOYSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50311887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50311887 (6-bromo-N-(3-chlorophenyl)quinazolin-4-amine | CHE...) Show SMILES Clc1cccc(Nc2ncnc3ccc(Br)cc23)c1 Show InChI InChI=1S/C14H9BrClN3/c15-9-4-5-13-12(6-9)14(18-8-17-13)19-11-3-1-2-10(16)7-11/h1-8H,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Displacement of [3H]3methoxy-5-(pyridin-2-ylethynyl)pyridine from rat mGluR5				Bioorg Med Chem Lett 19: 6623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.024 BindingDB Entry DOI: 10.7270/Q2TX3FHM
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50311887 (6-bromo-N-(3-chlorophenyl)quinazolin-4-amine | CHE...) Show SMILES Clc1cccc(Nc2ncnc3ccc(Br)cc23)c1 Show InChI InChI=1S/C14H9BrClN3/c15-9-4-5-13-12(6-9)14(18-8-17-13)19-11-3-1-2-10(16)7-11/h1-8H,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	256	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR5 expressed in HEK293 cells by calcium mobilization assay				Bioorg Med Chem Lett 19: 6623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.024 BindingDB Entry DOI: 10.7270/Q2TX3FHM
					More data for this Ligand-Target Pair
Prion protein (Homo sapiens (Human))	BDBM50311887 (6-bromo-N-(3-chlorophenyl)quinazolin-4-amine | CHE...) Show SMILES Clc1cccc(Nc2ncnc3ccc(Br)cc23)c1 Show InChI InChI=1S/C14H9BrClN3/c15-9-4-5-13-12(6-9)14(18-8-17-13)19-11-3-1-2-10(16)7-11/h1-8H,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2HM573M
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (RAT)	BDBM50311887 (6-bromo-N-(3-chlorophenyl)quinazolin-4-amine | CHE...) Show SMILES Clc1cccc(Nc2ncnc3ccc(Br)cc23)c1 Show InChI InChI=1S/C14H9BrClN3/c15-9-4-5-13-12(6-9)14(18-8-17-13)19-11-3-1-2-10(16)7-11/h1-8H,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1 expressed in BHK cells by calcium mobilization assay				Bioorg Med Chem Lett 19: 6623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.024 BindingDB Entry DOI: 10.7270/Q2TX3FHM
					More data for this Ligand-Target Pair