BDBM50282617 6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-4,5-dihydropyridazin-3(2H)-one::CHEMBL24646::dl-Pimobendan::pimobendan

SMILES: COc1ccc(cc1)-c1nc2ccc(cc2[nH]1)C1=NNC(=O)CC1C

InChI Key: InChIKey=GLBJJMFZWDBELO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282617   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50282617 (6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-met...) Show SMILES COc1ccc(cc1)-c1nc2ccc(cc2[nH]1)C1=NNC(=O)CC1C |t:20| Show InChI InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of binding against Angiotensin II receptor, type 1 in bovine adrenal cortex				Bioorg Med Chem Lett 4: 1297-1302 (1994) Article DOI: 10.1016/S0960-894X(01)80348-6 BindingDB Entry DOI: 10.7270/Q2G44QRD
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50282617 (6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-met...) Show SMILES COc1ccc(cc1)-c1nc2ccc(cc2[nH]1)C1=NNC(=O)CC1C |t:20| Show InChI InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of phosphodiesterase 3				Citation and Details Article DOI: 10.1016/S0960-894X(01)80288-2 BindingDB Entry DOI: 10.7270/Q2HX1GD4
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50282617 (6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-met...) Show SMILES COc1ccc(cc1)-c1nc2ccc(cc2[nH]1)C1=NNC(=O)CC1C |t:20| Show InChI InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of phosphodiesterase 3				Citation and Details Article DOI: 10.1016/S0960-894X(01)80288-2 BindingDB Entry DOI: 10.7270/Q2HX1GD4
					More data for this Ligand-Target Pair