BDBM50049572 1,3-benzodiazine::1,3-diazanaphthalene::5,6-benzopyrimidine::CHEMBL301359::Chinazolin::benzo[a]pyrimidine::phenmiazine::quinazoline

SMILES: c1ccc2ncncc2c1

InChI Key: InChIKey=JWVCLYRUEFBMGU-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50049572 (1,3-benzodiazine | 1,3-diazanaphthalene | 5,6-benz...) Show SMILES c1ccc2ncncc2c1 Show InChI InChI=1S/C8H6N2/c1-2-4-8-7(3-1)5-9-6-10-8/h1-6H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells				J Med Chem 39: 1823-35 (1996) Article DOI: 10.1021/jm9508651 BindingDB Entry DOI: 10.7270/Q2X928GF
					More data for this Ligand-Target Pair