BDBM50313764 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one::CHEMBL453290::Kaempferol-3-O-beta-D-galactoside::Trifolin::kaempferol-3-O-beta-galactopyranoside
SMILES: OC[C@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@H]1O
InChI Key: InChIKey=VLAZVXDNDNYUKJ-DTGCRPNFSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin-converting enzyme (Oryctolagus cuniculus) | BDBM50313764 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3-((2S,3R,4S,5R,...) | MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
India Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of rabbit lung ACE assessed as reduction in hippuryl-histidyl-leucine substrate by colorimetric assay | Bioorg Med Chem 19: 4772-81 (2011) Article DOI: 10.1016/j.bmc.2011.06.085 BindingDB Entry DOI: 10.7270/Q27M089B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Oryctolagus cuniculus) | BDBM50313764 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3-((2S,3R,4S,5R,...) | MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calabria Curated by ChEMBL | Assay Description Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysis | Bioorg Med Chem Lett 20: 1990-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.113 BindingDB Entry DOI: 10.7270/Q2G73DW4 | |||||||||||
More data for this Ligand-Target Pair |