BDBM100835 US8507533, 150

SMILES: CCCC(Oc1cnc(c(C)c1)-n1cc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key: InChIKey=UZLOLFXEOGTMRG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-glucagon (Homo sapiens (Human))	BDBM100835 (US8507533, 150) Show SMILES CCCC(Oc1cnc(c(C)c1)-n1cc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H25F3N4O4/c1-3-4-20(16-5-7-17(8-6-16)23(34)28-10-9-21(32)33)35-19-11-15(2)22(29-13-19)31-14-18(12-30-31)24(25,26)27/h5-8,11-14,20H,3-4,9-10H2,1-2H3,(H,28,34)(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	446	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Inc. US Patent					Assay Description The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptors.				US Patent US8507533 (2013) BindingDB Entry DOI: 10.7270/Q23R0RGH
					More data for this Ligand-Target Pair