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SMILES: Cc1cc(OC(C2CC(C)(C)C2)c2ccc(cc2)C(=O)NCCC(O)=O)cc(C)c1-n1cc(cn1)C(F)(F)F

InChI Key: InChIKey=FAWURTSYOBLHRC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100837   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Pro-glucagon


(Homo sapiens (Human))		BDBM100837
PNG
(US8507533, 152)
Show SMILES Cc1cc(OC(C2CC(C)(C)C2)c2ccc(cc2)C(=O)NCCC(O)=O)cc(C)c1-n1cc(cn1)C(F)(F)F
Show InChI InChI=1S/C29H32F3N3O4/c1-17-11-23(12-18(2)25(17)35-16-22(15-34-35)29(30,31)32)39-26(21-13-28(3,4)14-21)19-5-7-20(8-6-19)27(38)33-10-9-24(36)37/h5-8,11-12,15-16,21,26H,9-10,13-14H2,1-4H3,(H,33,38)(H,36,37)
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Similars
US Patent
 35.2n/an/an/an/an/an/a7.4n/a



Pfizer Inc.

US Patent


Assay Description
The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptors.

US Patent US8507533 (2013)


BindingDB Entry DOI: 10.7270/Q23R0RGH
More data for this
Ligand-Target Pair