Found 3 hits for monomerid = 100883 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM100883
(US8507510, 1.10)Show SMILES C[C@@H](Nc1nc(Nc2ccc(cc2)S(=O)(=NS(=O)(=O)CC[Si](C)(C)C)C2CCCC2)ncc1Br)C(C)(C)O |r| Show InChI InChI=1S/C25H40BrN5O4S2Si/c1-18(25(2,3)32)28-23-22(26)17-27-24(30-23)29-19-11-13-21(14-12-19)37(35,20-9-7-8-10-20)31-36(33,34)15-16-38(4,5)6/h11-14,17-18,20,32H,7-10,15-16H2,1-6H3,(H2,27,28,29,30)/t18-,37?/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH
US Patent
| Assay Description Kinase assay using either CDK1, CDK2 or VEGFR-2. |
US Patent US8507510 (2013)
BindingDB Entry DOI: 10.7270/Q2V69H76 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM100883
(US8507510, 1.10)Show SMILES C[C@@H](Nc1nc(Nc2ccc(cc2)S(=O)(=NS(=O)(=O)CC[Si](C)(C)C)C2CCCC2)ncc1Br)C(C)(C)O |r| Show InChI InChI=1S/C25H40BrN5O4S2Si/c1-18(25(2,3)32)28-23-22(26)17-27-24(30-23)29-19-11-13-21(14-12-19)37(35,20-9-7-8-10-20)31-36(33,34)15-16-38(4,5)6/h11-14,17-18,20,32H,7-10,15-16H2,1-6H3,(H2,27,28,29,30)/t18-,37?/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH
US Patent
| Assay Description Kinase assay using either CDK1, CDK2 or VEGFR-2. |
US Patent US8507510 (2013)
BindingDB Entry DOI: 10.7270/Q2V69H76 |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM100883
(US8507510, 1.10)Show SMILES C[C@@H](Nc1nc(Nc2ccc(cc2)S(=O)(=NS(=O)(=O)CC[Si](C)(C)C)C2CCCC2)ncc1Br)C(C)(C)O |r| Show InChI InChI=1S/C25H40BrN5O4S2Si/c1-18(25(2,3)32)28-23-22(26)17-27-24(30-23)29-19-11-13-21(14-12-19)37(35,20-9-7-8-10-20)31-36(33,34)15-16-38(4,5)6/h11-14,17-18,20,32H,7-10,15-16H2,1-6H3,(H2,27,28,29,30)/t18-,37?/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH
US Patent
| Assay Description Kinase assay using either CDK1, CDK2 or VEGFR-2. |
US Patent US8507510 (2013)
BindingDB Entry DOI: 10.7270/Q2V69H76 |
More data for this Ligand-Target Pair | |