BDBM101383 US9695152, 4::US9695152, 5

SMILES: CN(C1CCN(C1)S(=O)(=O)C1CC1)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C

InChI Key: InChIKey=SFUQSKFZFRDQEC-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 101383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM101383 (US9695152, 4 | US9695152, 5) Show SMILES CN(C1CCN(C1)S(=O)(=O)C1CC1)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C23H27ClN4O3S/c1-23(2)21-10-15(24)4-7-20(21)22(29)28(23)18-11-17(12-25-13-18)26(3)16-8-9-27(14-16)32(30,31)19-5-6-19/h4,7,10-13,16,19H,5-6,8-9,14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM101383 (US9695152, 4 | US9695152, 5) Show SMILES CN(C1CCN(C1)S(=O)(=O)C1CC1)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C23H27ClN4O3S/c1-23(2)21-10-15(24)4-7-20(21)22(29)28(23)18-11-17(12-25-13-18)26(3)16-8-9-27(14-16)32(30,31)19-5-6-19/h4,7,10-13,16,19H,5-6,8-9,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	133	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM101383 (US9695152, 4 | US9695152, 5) Show SMILES CN(C1CCN(C1)S(=O)(=O)C1CC1)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C23H27ClN4O3S/c1-23(2)21-10-15(24)4-7-20(21)22(29)28(23)18-11-17(12-25-13-18)26(3)16-8-9-27(14-16)32(30,31)19-5-6-19/h4,7,10-13,16,19H,5-6,8-9,14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM101383 (US9695152, 4 | US9695152, 5) Show SMILES CN(C1CCN(C1)S(=O)(=O)C1CC1)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C23H27ClN4O3S/c1-23(2)21-10-15(24)4-7-20(21)22(29)28(23)18-11-17(12-25-13-18)26(3)16-8-9-27(14-16)32(30,31)19-5-6-19/h4,7,10-13,16,19H,5-6,8-9,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ
					More data for this Ligand-Target Pair