null

SMILES: Cc1noc(C)c1C(=O)N1CC(C1)Nc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C

InChI Key: InChIKey=GERLZUOPRCYPTJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM101402 (US9695152, 23) Show SMILES Cc1noc(C)c1C(=O)N1CC(C1)Nc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C24H24ClN5O3/c1-13-21(14(2)33-28-13)23(32)29-11-17(12-29)27-16-8-18(10-26-9-16)30-22(31)19-6-5-15(25)7-20(19)24(30,3)4/h5-10,17,27H,11-12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	5.95E+3	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM101402 (US9695152, 23) Show SMILES Cc1noc(C)c1C(=O)N1CC(C1)Nc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C24H24ClN5O3/c1-13-21(14(2)33-28-13)23(32)29-11-17(12-29)27-16-8-18(10-26-9-16)30-22(31)19-6-5-15(25)7-20(19)24(30,3)4/h5-10,17,27H,11-12H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ
					More data for this Ligand-Target Pair