BDBM101408 US9695152, 29::US9695152, 30
SMILES: C[C@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)S(=O)(=O)C2CC2)c1
InChI Key: InChIKey=MBEXZLOOZVYCDP-GFCCVEGCSA-N
Data: 4 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human)) | BDBM101408 (US9695152, 29 | US9695152, 30) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... | US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM101408 (US9695152, 29 | US9695152, 30) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 652 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... | US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human)) | BDBM101408 (US9695152, 29 | US9695152, 30) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... | US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM101408 (US9695152, 29 | US9695152, 30) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 5.81E+3 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... | US Patent US9695152 (2017) BindingDB Entry DOI: 10.7270/Q2FN14BQ | |||||||||||
More data for this Ligand-Target Pair |