BDBM101649 US9695160, 13::US9796707, Compound 13

SMILES: FC(F)(F)c1ccc(N2CCN(Cc3cccnc3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1

InChI Key: InChIKey=UHCHNGAAVWVTIB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase SRPK1 (Homo sapiens (Human))	BDBM101649 (US9695160, 13 | US9796707, Compound 13) Show SMILES FC(F)(F)c1ccc(N2CCN(Cc3cccnc3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1 Show InChI InChI=1S/C27H24F3N5O2/c28-27(29,30)21-3-4-23(35-14-12-34(13-15-35)18-19-2-1-9-32-17-19)22(16-21)33-26(36)25-6-5-24(37-25)20-7-10-31-11-8-20/h1-11,16-17H,12-15,18H2,(H,33,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17.2	n/a	n/a	n/a	n/a	n/a	n/a
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9796707 (2017) BindingDB Entry DOI: 10.7270/Q2125VTM
					More data for this Ligand-Target Pair
SRSF protein kinase 1 (SRPK1) (Homo sapiens (Human))	BDBM101649 (US9695160, 13 | US9796707, Compound 13) Show SMILES FC(F)(F)c1ccc(N2CCN(Cc3cccnc3)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1 Show InChI InChI=1S/C27H24F3N5O2/c28-27(29,30)21-3-4-23(35-14-12-34(13-15-35)18-19-2-1-9-32-17-19)22(16-21)33-26(36)25-6-5-24(37-25)20-7-10-31-11-8-20/h1-11,16-17H,12-15,18H2,(H,33,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	30
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9695160 (2017) BindingDB Entry DOI: 10.7270/Q2639MW1
					More data for this Ligand-Target Pair