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SMILES: Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccccn2)CC1)C(F)(F)F

InChI Key: InChIKey=LLPZOGAWNMGFNA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SRSF protein kinase 1 (Homo sapiens (Human))	BDBM101659 (US9695160, 16 | US9796707, Compound 16) Show SMILES Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccccn2)CC1)C(F)(F)F Show InChI InChI=1S/C23H23F3N4O2/c1-16-5-8-21(32-16)22(31)28-19-14-17(23(24,25)26)6-7-20(19)30-12-10-29(11-13-30)15-18-4-2-3-9-27-18/h2-9,14H,10-13,15H2,1H3,(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38.2	n/a	n/a	n/a	n/a	n/a	n/a
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9796707 (2017) BindingDB Entry DOI: 10.7270/Q2125VTM
					More data for this Ligand-Target Pair
SRSF protein kinase 1 (Homo sapiens (Human))	BDBM101659 (US9695160, 16 | US9796707, Compound 16) Show SMILES Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccccn2)CC1)C(F)(F)F Show InChI InChI=1S/C23H23F3N4O2/c1-16-5-8-21(32-16)22(31)28-19-14-17(23(24,25)26)6-7-20(19)30-12-10-29(11-13-30)15-18-4-2-3-9-27-18/h2-9,14H,10-13,15H2,1H3,(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	30
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9695160 (2017) BindingDB Entry DOI: 10.7270/Q2639MW1
					More data for this Ligand-Target Pair