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BDBM101691 US8530504, 53

SMILES: COCCN(C1CCCC1)c1c(OC)nn2c(csc12)-c1c(OC)cc(COC)cc1OC

InChI Key: InChIKey=QMYORRBLPDQGHG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101691   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))		BDBM101691
PNG
(US8530504, 53)
Show SMILES COCCN(C1CCCC1)c1c(OC)nn2c(csc12)-c1c(OC)cc(COC)cc1OC |(-6.47,3.14,;-5.38,4.23,;-3.9,3.83,;-2.81,4.92,;-1.32,4.52,;-.23,5.61,;1.31,5.61,;1.79,7.08,;.54,7.98,;-.71,7.08,;-.92,3.04,;-1.83,1.79,;-3.37,1.79,;-4.14,.46,;-.92,.54,;.54,1.02,;2.01,.54,;2.91,1.79,;2.01,3.04,;.54,2.56,;2.41,-.94,;3.9,-1.34,;4.98,-.25,;6.47,-.65,;4.29,-2.83,;3.2,-3.92,;3.6,-5.41,;2.51,-6.49,;2.91,-7.98,;1.72,-3.52,;1.32,-2.03,;-.17,-1.63,;-1.26,-2.72,)|
Show InChI InChI=1S/C24H33N3O5S/c1-28-11-10-26(17-8-6-7-9-17)22-23(32-5)25-27-18(15-33-24(22)27)21-19(30-3)12-16(14-29-2)13-20(21)31-4/h12-13,15,17H,6-11,14H2,1-5H3
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Similars
US Patent
n/an/a 18n/an/an/an/an/an/a



Eisai R&D Management Co., Ltd.

US Patent


Assay Description
A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.

US Patent US8530504 (2013)


BindingDB Entry DOI: 10.7270/Q29885NS
More data for this
Ligand-Target Pair