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BDBM101719 US8530504, 83

SMILES: CCCCN(C1CCOCC1)c1c(OCC)nn2c(csc12)-c1c(OC)cc(COC)cc1OC

InChI Key: InChIKey=WBKJVKIORNBGJU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101719   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))		BDBM101719
PNG
(US8530504, 83)
Show SMILES CCCCN(C1CCOCC1)c1c(OCC)nn2c(csc12)-c1c(OC)cc(COC)cc1OC |(3.49,5.75,;2,6.15,;.91,5.06,;-.57,5.46,;-1.66,4.37,;-3.15,4.77,;-4.24,3.68,;-5.73,4.08,;-6.13,5.56,;-5.04,6.65,;-3.55,6.25,;-1.27,2.88,;-2.17,1.63,;-3.71,1.63,;-4.48,.3,;-6.02,.3,;-1.27,.39,;.2,.86,;1.66,.39,;2.57,1.63,;1.66,2.88,;.2,2.4,;2.06,-1.1,;.97,-2.19,;-.51,-1.79,;-1.6,-2.88,;1.37,-3.68,;2.86,-4.08,;3.26,-5.56,;2.17,-6.65,;.68,-6.25,;3.95,-2.99,;3.55,-1.5,;4.64,-.41,;6.13,-.81,)|
Show InChI InChI=1S/C26H37N3O5S/c1-6-8-11-28(19-9-12-33-13-10-19)24-25(34-7-2)27-29-20(17-35-26(24)29)23-21(31-4)14-18(16-30-3)15-22(23)32-5/h14-15,17,19H,6-13,16H2,1-5H3
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Similars
US Patent
n/an/a 47n/an/an/an/an/an/a



Eisai R&D Management Co., Ltd.

US Patent


Assay Description
A binding competition experiment with CRF was conducted by the SPA (GE Healthcare) method using a 96-well plate.

US Patent US8530504 (2013)


BindingDB Entry DOI: 10.7270/Q29885NS
More data for this
Ligand-Target Pair