Found 4 hits for monomerid = 102143 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM102143
(US8530648, 40)Show SMILES Cc1cc2c(CN3CCCC4(CCN(CC4)c4cnc5ccccc5n4)C3=O)cccc2[nH]1 Show InChI InChI=1S/C27H29N5O/c1-19-16-21-20(6-4-9-22(21)29-19)18-32-13-5-10-27(26(32)33)11-14-31(15-12-27)25-17-28-23-7-2-3-8-24(23)30-25/h2-4,6-9,16-17,29H,5,10-15,18H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description FLIPR assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin receptor type 1
(Homo sapiens (Human)) | BDBM102143
(US8530648, 40)Show SMILES Cc1cc2c(CN3CCCC4(CCN(CC4)c4cnc5ccccc5n4)C3=O)cccc2[nH]1 Show InChI InChI=1S/C27H29N5O/c1-19-16-21-20(6-4-9-22(21)29-19)18-32-13-5-10-27(26(32)33)11-14-31(15-12-27)25-17-28-23-7-2-3-8-24(23)30-25/h2-4,6-9,16-17,29H,5,10-15,18H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 365 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description FLIPR assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM102143
(US8530648, 40)Show SMILES Cc1cc2c(CN3CCCC4(CCN(CC4)c4cnc5ccccc5n4)C3=O)cccc2[nH]1 Show InChI InChI=1S/C27H29N5O/c1-19-16-21-20(6-4-9-22(21)29-19)18-32-13-5-10-27(26(32)33)11-14-31(15-12-27)25-17-28-23-7-2-3-8-24(23)30-25/h2-4,6-9,16-17,29H,5,10-15,18H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | 62 | n/a | n/a | n/a | 7.5 | n/a |
Novartis AG
US Patent
| Assay Description Radioligand binding assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin receptor type 1
(Homo sapiens (Human)) | BDBM102143
(US8530648, 40)Show SMILES Cc1cc2c(CN3CCCC4(CCN(CC4)c4cnc5ccccc5n4)C3=O)cccc2[nH]1 Show InChI InChI=1S/C27H29N5O/c1-19-16-21-20(6-4-9-22(21)29-19)18-32-13-5-10-27(26(32)33)11-14-31(15-12-27)25-17-28-23-7-2-3-8-24(23)30-25/h2-4,6-9,16-17,29H,5,10-15,18H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | 776 | n/a | n/a | n/a | 7.5 | n/a |
Novartis AG
US Patent
| Assay Description Radioligand binding assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |