BDBM102153 US8530648, 50

SMILES: FC(F)(F)c1ccccc1CN1CCCC2(CCN(CC2)c2cnc3ccccc3n2)C1=O

InChI Key: InChIKey=LAZFQQSOMFUUKF-UHFFFAOYSA-N

Data: 2 KI  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 102153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM102153 (US8530648, 50) Show SMILES FC(F)(F)c1ccccc1CN1CCCC2(CCN(CC2)c2cnc3ccccc3n2)C1=O Show InChI InChI=1S/C25H25F3N4O/c26-25(27,28)19-7-2-1-6-18(19)17-32-13-5-10-24(23(32)33)11-14-31(15-12-24)22-16-29-20-8-3-4-9-21(20)30-22/h1-4,6-9,16H,5,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	280	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Novartis AG US Patent					Assay Description FLIPR assay using orexin receptor.				US Patent US8530648 (2013) BindingDB Entry DOI: 10.7270/Q2SB44DR
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM102153 (US8530648, 50) Show SMILES FC(F)(F)c1ccccc1CN1CCCC2(CCN(CC2)c2cnc3ccccc3n2)C1=O Show InChI InChI=1S/C25H25F3N4O/c26-25(27,28)19-7-2-1-6-18(19)17-32-13-5-10-24(23(32)33)11-14-31(15-12-24)22-16-29-20-8-3-4-9-21(20)30-22/h1-4,6-9,16H,5,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Novartis AG US Patent					Assay Description FLIPR assay using orexin receptor.				US Patent US8530648 (2013) BindingDB Entry DOI: 10.7270/Q2SB44DR
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM102153 (US8530648, 50) Show SMILES FC(F)(F)c1ccccc1CN1CCCC2(CCN(CC2)c2cnc3ccccc3n2)C1=O Show InChI InChI=1S/C25H25F3N4O/c26-25(27,28)19-7-2-1-6-18(19)17-32-13-5-10-24(23(32)33)11-14-31(15-12-24)22-16-29-20-8-3-4-9-21(20)30-22/h1-4,6-9,16H,5,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	7.5	n/a
Novartis AG US Patent					Assay Description Radioligand binding assay using orexin receptor.				US Patent US8530648 (2013) BindingDB Entry DOI: 10.7270/Q2SB44DR
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM102153 (US8530648, 50) Show SMILES FC(F)(F)c1ccccc1CN1CCCC2(CCN(CC2)c2cnc3ccccc3n2)C1=O Show InChI InChI=1S/C25H25F3N4O/c26-25(27,28)19-7-2-1-6-18(19)17-32-13-5-10-24(23(32)33)11-14-31(15-12-24)22-16-29-20-8-3-4-9-21(20)30-22/h1-4,6-9,16H,5,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	4.48E+3	n/a	n/a	n/a	7.5	n/a
Novartis AG US Patent					Assay Description Radioligand binding assay using orexin receptor.				US Patent US8530648 (2013) BindingDB Entry DOI: 10.7270/Q2SB44DR
					More data for this Ligand-Target Pair