Found 4 hits for monomerid = 102157 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM102157
(US8530648, 54)Show SMILES Clc1cccc(CN2CCCC3(CCN(CC3)c3cnc4ccccc4n3)C2=O)c1 Show InChI InChI=1S/C24H25ClN4O/c25-19-6-3-5-18(15-19)17-29-12-4-9-24(23(29)30)10-13-28(14-11-24)22-16-26-20-7-1-2-8-21(20)27-22/h1-3,5-8,15-16H,4,9-14,17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 84 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description FLIPR assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin receptor type 1
(Homo sapiens (Human)) | BDBM102157
(US8530648, 54)Show SMILES Clc1cccc(CN2CCCC3(CCN(CC3)c3cnc4ccccc4n3)C2=O)c1 Show InChI InChI=1S/C24H25ClN4O/c25-19-6-3-5-18(15-19)17-29-12-4-9-24(23(29)30)10-13-28(14-11-24)22-16-26-20-7-1-2-8-21(20)27-22/h1-3,5-8,15-16H,4,9-14,17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 740 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description FLIPR assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM102157
(US8530648, 54)Show SMILES Clc1cccc(CN2CCCC3(CCN(CC3)c3cnc4ccccc4n3)C2=O)c1 Show InChI InChI=1S/C24H25ClN4O/c25-19-6-3-5-18(15-19)17-29-12-4-9-24(23(29)30)10-13-28(14-11-24)22-16-26-20-7-1-2-8-21(20)27-22/h1-3,5-8,15-16H,4,9-14,17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | 169 | n/a | n/a | n/a | 7.5 | n/a |
Novartis AG
US Patent
| Assay Description Radioligand binding assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin receptor type 1
(Homo sapiens (Human)) | BDBM102157
(US8530648, 54)Show SMILES Clc1cccc(CN2CCCC3(CCN(CC3)c3cnc4ccccc4n3)C2=O)c1 Show InChI InChI=1S/C24H25ClN4O/c25-19-6-3-5-18(15-19)17-29-12-4-9-24(23(29)30)10-13-28(14-11-24)22-16-26-20-7-1-2-8-21(20)27-22/h1-3,5-8,15-16H,4,9-14,17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | 702 | n/a | n/a | n/a | 7.5 | n/a |
Novartis AG
US Patent
| Assay Description Radioligand binding assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |