Found 4 hits for monomerid = 102176 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM102176
(US8530648, 102)Show SMILES O=C1N(Cc2cccc(c2)-n2ccnn2)CCCC11CCN(CC1)c1cnc2ccccc2n1 Show InChI InChI=1S/C26H27N7O/c34-25-26(10-14-31(15-11-26)24-18-27-22-7-1-2-8-23(22)29-24)9-4-13-32(25)19-20-5-3-6-21(17-20)33-16-12-28-30-33/h1-3,5-8,12,16-18H,4,9-11,13-15,19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 247 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description FLIPR assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM102176
(US8530648, 102)Show SMILES O=C1N(Cc2cccc(c2)-n2ccnn2)CCCC11CCN(CC1)c1cnc2ccccc2n1 Show InChI InChI=1S/C26H27N7O/c34-25-26(10-14-31(15-11-26)24-18-27-22-7-1-2-8-23(22)29-24)9-4-13-32(25)19-20-5-3-6-21(17-20)33-16-12-28-30-33/h1-3,5-8,12,16-18H,4,9-11,13-15,19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Novartis AG
US Patent
| Assay Description FLIPR assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin receptor type 2
(Homo sapiens (Human)) | BDBM102176
(US8530648, 102)Show SMILES O=C1N(Cc2cccc(c2)-n2ccnn2)CCCC11CCN(CC1)c1cnc2ccccc2n1 Show InChI InChI=1S/C26H27N7O/c34-25-26(10-14-31(15-11-26)24-18-27-22-7-1-2-8-23(22)29-24)9-4-13-32(25)19-20-5-3-6-21(17-20)33-16-12-28-30-33/h1-3,5-8,12,16-18H,4,9-11,13-15,19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | 473 | n/a | n/a | n/a | 7.5 | n/a |
Novartis AG
US Patent
| Assay Description Radioligand binding assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM102176
(US8530648, 102)Show SMILES O=C1N(Cc2cccc(c2)-n2ccnn2)CCCC11CCN(CC1)c1cnc2ccccc2n1 Show InChI InChI=1S/C26H27N7O/c34-25-26(10-14-31(15-11-26)24-18-27-22-7-1-2-8-23(22)29-24)9-4-13-32(25)19-20-5-3-6-21(17-20)33-16-12-28-30-33/h1-3,5-8,12,16-18H,4,9-11,13-15,19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | 1.29E+3 | n/a | n/a | n/a | 7.5 | n/a |
Novartis AG
US Patent
| Assay Description Radioligand binding assay using orexin receptor. |
US Patent US8530648 (2013)
BindingDB Entry DOI: 10.7270/Q2SB44DR |
More data for this Ligand-Target Pair | |