BDBM103272 US8546389, 179

SMILES: CNC(=O)c1n(nc2cc(N(CCCNC(=O)c3nonc3C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1

InChI Key: InChIKey=ICDNOXRGCRALSG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM103272 (US8546389, 179) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)c3nonc3C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C26H28BrN7O5S/c1-15-23(32-39-31-15)25(35)29-11-4-12-33(40(3,37)38)22-14-21-20(13-19(22)16-5-6-16)24(26(36)28-2)34(30-21)18-9-7-17(27)8-10-18/h7-10,13-14,16H,4-6,11-12H2,1-3H3,(H,28,36)(H,29,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM103272 (US8546389, 179) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)c3nonc3C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C26H28BrN7O5S/c1-15-23(32-39-31-15)25(35)29-11-4-12-33(40(3,37)38)22-14-21-20(13-19(22)16-5-6-16)24(26(36)28-2)34(30-21)18-9-7-17(27)8-10-18/h7-10,13-14,16H,4-6,11-12H2,1-3H3,(H,28,36)(H,29,35)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair