BDBM103278 US8546389, 216

SMILES: CNC(=O)c1n(nc2cc(N(CCCNC(=O)[C@H]3CCC[C@@H]3C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1

InChI Key: InChIKey=DGWUFNYVRVBRDE-VXKWHMMOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM103278 (US8546389, 216) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)[C@H]3CCC[C@@H]3C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 |r| Show InChI InChI=1S/C30H36BrN5O6S/c1-32-29(38)27-24-16-23(18-8-9-18)26(17-25(24)34-36(27)20-12-10-19(31)11-13-20)35(43(3,40)41)15-5-14-33-28(37)21-6-4-7-22(21)30(39)42-2/h10-13,16-18,21-22H,4-9,14-15H2,1-3H3,(H,32,38)(H,33,37)/t21-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM103278 (US8546389, 216) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)[C@H]3CCC[C@@H]3C(=O)OC)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 |r| Show InChI InChI=1S/C30H36BrN5O6S/c1-32-29(38)27-24-16-23(18-8-9-18)26(17-25(24)34-36(27)20-12-10-19(31)11-13-20)35(43(3,40)41)15-5-14-33-28(37)21-6-4-7-22(21)30(39)42-2/h10-13,16-18,21-22H,4-9,14-15H2,1-3H3,(H,32,38)(H,33,37)/t21-,22-/m0/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair