BDBM103334 US8546392, 19

SMILES: CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1

InChI Key: InChIKey=WCLQUDCFQAVYPS-ACCUITESSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 103334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human))	BDBM103334 (US8546392, 19) Show SMILES CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1 Show InChI InChI=1S/C23H22O4/c1-4-27-23(24)13-11-21-20-10-8-17(14-18(20)9-12-22(21)26-3)16-6-5-7-19(15-16)25-2/h5-15H,4H2,1-3H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universitaet des Saarlandes US Patent					Assay Description The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...				US Patent US8546392 (2013) BindingDB Entry DOI: 10.7270/Q2WW7G8P
					More data for this Ligand-Target Pair
17-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM103334 (US8546392, 19) Show SMILES CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1 Show InChI InChI=1S/C23H22O4/c1-4-27-23(24)13-11-21-20-10-8-17(14-18(20)9-12-22(21)26-3)16-6-5-7-19(15-16)25-2/h5-15H,4H2,1-3H3/b13-11+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitaet des Saarlandes US Patent					Assay Description The determination of IC50 values was performed with enzyme isolated from human placenta (Luu-The, V. et al., J. Steroid Biochem. Mol. Biol., 55:581-5...				US Patent US8546392 (2013) BindingDB Entry DOI: 10.7270/Q2WW7G8P
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM103334 (US8546392, 19) Show SMILES CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1 Show InChI InChI=1S/C23H22O4/c1-4-27-23(24)13-11-21-20-10-8-17(14-18(20)9-12-22(21)26-3)16-6-5-7-19(15-16)25-2/h5-15H,4H2,1-3H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitaet des Saarlandes US Patent					Assay Description Inhibition assay using P450 CYP enzymes.				US Patent US8546392 (2013) BindingDB Entry DOI: 10.7270/Q2WW7G8P
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM103334 (US8546392, 19) Show SMILES CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1 Show InChI InChI=1S/C23H22O4/c1-4-27-23(24)13-11-21-20-10-8-17(14-18(20)9-12-22(21)26-3)16-6-5-7-19(15-16)25-2/h5-15H,4H2,1-3H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitaet des Saarlandes US Patent					Assay Description Inhibition assay using P450 CYP enzymes.				US Patent US8546392 (2013) BindingDB Entry DOI: 10.7270/Q2WW7G8P
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM103334 (US8546392, 19) Show SMILES CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1 Show InChI InChI=1S/C23H22O4/c1-4-27-23(24)13-11-21-20-10-8-17(14-18(20)9-12-22(21)26-3)16-6-5-7-19(15-16)25-2/h5-15H,4H2,1-3H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitaet des Saarlandes US Patent					Assay Description Inhibition assay using P450 CYP enzymes.				US Patent US8546392 (2013) BindingDB Entry DOI: 10.7270/Q2WW7G8P
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM103334 (US8546392, 19) Show SMILES CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1 Show InChI InChI=1S/C23H22O4/c1-4-27-23(24)13-11-21-20-10-8-17(14-18(20)9-12-22(21)26-3)16-6-5-7-19(15-16)25-2/h5-15H,4H2,1-3H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitaet des Saarlandes US Patent					Assay Description Inhibition assay using P450 CYP enzymes.				US Patent US8546392 (2013) BindingDB Entry DOI: 10.7270/Q2WW7G8P
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM103334 (US8546392, 19) Show SMILES CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1 Show InChI InChI=1S/C23H22O4/c1-4-27-23(24)13-11-21-20-10-8-17(14-18(20)9-12-22(21)26-3)16-6-5-7-19(15-16)25-2/h5-15H,4H2,1-3H3/b13-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitaet des Saarlandes US Patent					Assay Description Inhibition assay using P450 CYP enzymes.				US Patent US8546392 (2013) BindingDB Entry DOI: 10.7270/Q2WW7G8P
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM103334 (US8546392, 19) Show SMILES CCOC(=O)\C=C\c1c(OC)ccc2cc(ccc12)-c1cccc(OC)c1 Show InChI InChI=1S/C23H22O4/c1-4-27-23(24)13-11-21-20-10-8-17(14-18(20)9-12-22(21)26-3)16-6-5-7-19(15-16)25-2/h5-15H,4H2,1-3H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitaet des Saarlandes US Patent					Assay Description Inhibition assay using P450 CYP enzymes.				US Patent US8546392 (2013) BindingDB Entry DOI: 10.7270/Q2WW7G8P
					More data for this Ligand-Target Pair