null
SMILES: CC1(CCSC(N)=N1)c1cccc(OCCCc2ccccc2)c1
InChI Key: InChIKey=YJLHAJGUJSJUTR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM103416 (US8546380, 1010 | US8633188, 1010) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | 5.0 | 30 |
Shionogi & Co., Ltd. US Patent | Assay Description Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench... | US Patent US8633188 (2014) BindingDB Entry DOI: 10.7270/Q2FT8JQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM103416 (US8546380, 1010 | US8633188, 1010) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | 5.0 | 30 |
Shionogi & Co., Ltd. US Patent | Assay Description Inhibition assay using beta-Secretase activity. | US Patent US8546380 (2013) BindingDB Entry DOI: 10.7270/Q2HQ3XJ0 | |||||||||||
More data for this Ligand-Target Pair |