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BDBM106158 US9695174, 8A

SMILES: COC(=O)[C@H]1Cc2c([nH]c3cc(OC)c(OC)cc23)[C@H](CC(C)C)N1C(=O)[C@H](C)NC(=O)OC(C)(C)C

InChI Key: InChIKey=GXKJJZCZNQBHFC-HUYOIKENNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106158   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-binding cassette sub-family G member 2


(Homo sapiens (Human))
BDBM106158
PNG
(US9695174, 8A)
Show SMILES COC(=O)[C@H]1Cc2c([nH]c3cc(OC)c(OC)cc23)[C@H](CC(C)C)N1C(=O)[C@H](C)NC(=O)OC(C)(C)C |r|
Show InChI InChI=1/C27H39N3O7/c1-14(2)10-19-23-17(16-12-21(34-7)22(35-8)13-18(16)29-23)11-20(25(32)36-9)30(19)24(31)15(3)28-26(33)37-27(4,5)6/h12-15,19-20,29H,10-11H2,1-9H3,(H,28,33)/t15-,19-,20+/s2
PDB

NCI pathway
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/a7.437



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
To determine potency of compounds on inhibition of transporters, bi-directional transport studies are performed in Caco-2 cells (American Type Cultur...


US Patent US9695174 (2017)


BindingDB Entry DOI: 10.7270/Q2DN436B
More data for this
Ligand-Target Pair