BDBM106998 US8592579, 75

SMILES: C[C@]1(CCCN1c1nc(Nc2cc([nH]n2)C2CC2)c2cccn2n1)C(=O)NC1CCNC1

InChI Key: InChIKey=BBLNRBKDXAXPFZ-CEISFSOZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM106998 (US8592579, 75) Show SMILES C[C@]1(CCCN1c1nc(Nc2cc([nH]n2)C2CC2)c2cccn2n1)C(=O)NC1CCNC1 |r| Show InChI InChI=1S/C22H29N9O/c1-22(20(32)24-15-7-9-23-13-15)8-3-10-30(22)21-26-19(17-4-2-11-31(17)29-21)25-18-12-16(27-28-18)14-5-6-14/h2,4,11-12,14-15,23H,3,5-10,13H2,1H3,(H,24,32)(H2,25,26,27,28,29)/t15?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	462	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Kinase assay using IGF1-receptor.				US Patent US8592579 (2013) BindingDB Entry DOI: 10.7270/Q2SQ8Z12
					More data for this Ligand-Target Pair