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SMILES: O[C@H]1C[C@H](N(C1)c1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1)C(=O)NS(=O)(=O)C1CC1

InChI Key: InChIKey=GUPFHCRRNPJVRY-LRDDRELGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107014   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM107014
PNG
(US8592579, 215)
Show SMILES O[C@H]1C[C@H](N(C1)c1nc(Nc2cc(n[nH]2)C2CC2)c2cccn2n1)C(=O)NS(=O)(=O)C1CC1 |r|
Show InChI InChI=1S/C20H24N8O4S/c29-12-8-16(19(30)26-33(31,32)13-5-6-13)27(10-12)20-22-18(15-2-1-7-28(15)25-20)21-17-9-14(23-24-17)11-3-4-11/h1-2,7,9,11-13,16,29H,3-6,8,10H2,(H,26,30)(H2,21,22,23,24,25)/t12-,16-/m0/s1
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PC cid
PC sid
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US Patent
n/an/a 2.07E+3n/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Kinase assay using IGF1-receptor.

US Patent US8592579 (2013)


BindingDB Entry DOI: 10.7270/Q2SQ8Z12
More data for this
Ligand-Target Pair