BDBM108233 1‐[2‐(trifluoromethyl)phenyl]piperazine hydrochloride (Hit 1)

SMILES: FC(F)(F)c1ccccc1N1CCNCC1

InChI Key: InChIKey=VZUBMIDXJRGARE-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CD209 antigen (Homo sapiens (Human))	BDBM108233 (1‐[2‐(trifluoromethyl)phenyl]piperazin...) Show SMILES FC(F)(F)c1ccccc1N1CCNCC1 Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-3-1-2-4-10(9)16-7-5-15-6-8-16/h1-4,15H,5-8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.60E+6	n/a	n/a	n/a	n/a	n/a
Lavis Curated by ChEMBL					Assay Description Binding affinity to human DC-SIGN ECD expressed in Escherichia coli BL21(DE3) after 1 hr by Man-Fl-BSA assay				J Med Chem 62: 2218-2244 (2019) Article DOI: 10.1021/acs.jmedchem.8b01210
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [33-574] (Rattus norvegicus (Rat))	BDBM108233 (1‐[2‐(trifluoromethyl)phenyl]piperazin...) Show SMILES FC(F)(F)c1ccccc1N1CCNCC1 Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-3-1-2-4-10(9)16-7-5-15-6-8-16/h1-4,15H,5-8H2	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova (Italy).									Chembiochem 14: 1611-9 (2013) Article DOI: 10.1002/cbic.201300347 BindingDB Entry DOI: 10.7270/Q2DB80G3
					More data for this Ligand-Target Pair