BDBM108875 US8604016, 455::US9938267, Cmpd ID 455

SMILES: O=C(Cc1cccc(CCNC(=O)c2ccccc2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1

InChI Key: InChIKey=WXOBDDMGGFCIRY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108875 (US8604016, 455 | US9938267, Cmpd ID 455) Show SMILES O=C(Cc1cccc(CCNC(=O)c2ccccc2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C35H35N7O3S/c43-31(23-25-10-3-1-4-11-25)37-30-19-18-29(39-40-30)16-7-8-17-33-41-42-35(46-33)38-32(44)24-27-13-9-12-26(22-27)20-21-36-34(45)28-14-5-2-6-15-28/h1-6,9-15,18-19,22H,7-8,16-17,20-21,23-24H2,(H,36,45)(H,37,40,43)(H,38,42,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108875 (US8604016, 455 | US9938267, Cmpd ID 455) Show SMILES O=C(Cc1cccc(CCNC(=O)c2ccccc2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C35H35N7O3S/c43-31(23-25-10-3-1-4-11-25)37-30-19-18-29(39-40-30)16-7-8-17-33-41-42-35(46-33)38-32(44)24-27-13-9-12-26(22-27)20-21-36-34(45)28-14-5-2-6-15-28/h1-6,9-15,18-19,22H,7-8,16-17,20-21,23-24H2,(H,36,45)(H,37,40,43)(H,38,42,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair