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SMILES: Cc1[nH+]c(cs1)C#Cc1ccc(nc1)N1CCCC(F)C1

InChI Key: InChIKey=VAVROQILMNQMAG-UHFFFAOYSA-O

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109154   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM109154
PNG
(US8609852, 61)
Show SMILES Cc1[nH+]c(cs1)C#Cc1ccc(nc1)N1CCCC(F)C1
Show InChI InChI=1S/C16H16FN3S/c1-12-19-15(11-21-12)6-4-13-5-7-16(18-9-13)20-8-2-3-14(17)10-20/h5,7,9,11,14H,2-3,8,10H2,1H3/p+1
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Similars
US Patent
 12 -10.8n/an/an/an/an/an/a25



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...

US Patent US8609852 (2013)


BindingDB Entry DOI: 10.7270/Q27M06K3
More data for this
Ligand-Target Pair