BDBM109272 US8609698, 80

SMILES: Cc1ccccc1NC(=O)OCc1ccc(nc1)-n1[nH]cc(-c2cccnc2)c1=O

InChI Key: InChIKey=ZJRSIUKOOHUMJP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF) (Homo sapiens (Human))	BDBM109272 (US8609698, 80) Show SMILES Cc1ccccc1NC(=O)OCc1ccc(nc1)-n1[nH]cc(-c2cccnc2)c1=O Show InChI InChI=1S/C22H19N5O3/c1-15-5-2-3-7-19(15)26-22(29)30-14-16-8-9-20(24-11-16)27-21(28)18(13-25-27)17-6-4-10-23-12-17/h2-13,25H,14H2,1H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...				US Patent US8609698 (2013) BindingDB Entry DOI: 10.7270/Q2G44NZ8
					More data for this Ligand-Target Pair