BDBM10994 (1R)-1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-4-ol::4-hydroxy-N-propargyl-1(R)-aminoindan::R-4HPAI::rasagiline analog

SMILES: Oc1cccc2[C@@H](CCc12)NCC#C

InChI Key: InChIKey=MQJZMFWAGYASSM-LLVKDONJSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM10994 ((1R)-1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...) Show SMILES Oc1cccc2[C@@H](CCc12)NCC#C |r| Show InChI InChI=1S/C12H13NO/c1-2-8-13-11-7-6-10-9(11)4-3-5-12(10)14/h1,3-5,11,13-14H,6-8H2/t11-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	-7.77	n/a	n/a	n/a	n/a	n/a	7.5	25
University of Pavia					Assay Description MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ...				J Med Chem 48: 8148-54 (2005) Article DOI: 10.1021/jm0506266 BindingDB Entry DOI: 10.7270/Q2T151WC
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM10994 ((1R)-1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...) Show SMILES Oc1cccc2[C@@H](CCc12)NCC#C |r| Show InChI InChI=1S/C12H13NO/c1-2-8-13-11-7-6-10-9(11)4-3-5-12(10)14/h1,3-5,11,13-14H,6-8H2/t11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.10E+4	-6.15	n/a	n/a	n/a	n/a	n/a	7.5	25
University of Pavia					Assay Description MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ...				J Med Chem 48: 8148-54 (2005) Article DOI: 10.1021/jm0506266 BindingDB Entry DOI: 10.7270/Q2T151WC
					More data for this Ligand-Target Pair