BDBM111123 US10017516, Compound 2::US9682983, 2

SMILES: C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12

InChI Key: InChIKey=SHWKNOUREYUNBF-KDURUIRLSA-N

Data: 20 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 111123   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase receptor R3 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.5	n/a
The Brigham and Women's Hospital, Inc.; Dept. of Health and Human Services, National Institutes of Health US Patent					Assay Description Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...				US Patent US9682983 (2017) BindingDB Entry DOI: 10.7270/Q28S4N3R
					More data for this Ligand-Target Pair
Activin receptor type-1 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of ALK2 (unknown origin) using Ulight topo IIa (Thr 1342) peptide as substrate preincubated for 10 mins followed by substrate addition and...				Bioorg Med Chem Lett 28: 3356-3362 (2018) Article DOI: 10.1016/j.bmcl.2018.09.006 BindingDB Entry DOI: 10.7270/Q2NZ8BBT
					More data for this Ligand-Target Pair
Activin receptor-like kinase 3 (ALK-3) (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.10	n/a	n/a	n/a	n/a	7.5	n/a
The Brigham and Women's Hospital, Inc.; Dept. of Health and Human Services, National Institutes of Health US Patent					Assay Description Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...				US Patent US9682983 (2017) BindingDB Entry DOI: 10.7270/Q28S4N3R
					More data for this Ligand-Target Pair
Activin receptor type-1B (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	556	n/a	n/a	n/a	n/a	7.5	n/a
The Brigham and Women's Hospital, Inc.; Dept. of Health and Human Services, National Institutes of Health US Patent					Assay Description Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...				US Patent US9682983 (2017) BindingDB Entry DOI: 10.7270/Q28S4N3R
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	7.5	n/a
The Brigham and Women's Hospital, Inc.; Dept. of Health and Human Services, National Institutes of Health US Patent					Assay Description Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...				US Patent US9682983 (2017) BindingDB Entry DOI: 10.7270/Q28S4N3R
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	7.5	n/a
The Brigham and Women's Hospital, Inc.; Dept. of Health and Human Services, National Institutes of Health US Patent					Assay Description Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...				US Patent US9682983 (2017) BindingDB Entry DOI: 10.7270/Q28S4N3R
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 (ALK1) (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Activin receptor type-1 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Activin receptor-like kinase 3 (ALK-3) (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4) (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	556	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 (ALK1) (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Activin receptor type-1 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Activin receptor-like kinase 3 (ALK-3) (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4) (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	226	n/a	n/a	n/a	n/a	n/a	n/a
The Brigham and Women's Hospital, Inc. US Patent					Assay Description Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...				US Patent US10017516 (2018) BindingDB Entry DOI: 10.7270/Q20P12CN
					More data for this Ligand-Target Pair
Activin receptor-like kinase 3 (ALK-3) (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of ALK3 (unknown origin) using Ulight topo IIa (Thr 1342) peptide as substrate preincubated for 10 mins followed by substrate addition and...				Bioorg Med Chem Lett 28: 3356-3362 (2018) Article DOI: 10.1016/j.bmcl.2018.09.006 BindingDB Entry DOI: 10.7270/Q2NZ8BBT
					More data for this Ligand-Target Pair
Activin receptor type-1 (Homo sapiens (Human))	BDBM111123 (US10017516, Compound 2 | US9682983, 2) Show SMILES C[C@H]1CNC[C@@H](C)N1c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 |r| Show InChI InChI=1S/C27H26N6/c1-18-13-28-14-19(2)33(18)22-9-7-20(8-10-22)21-15-30-27-25(16-31-32(27)17-21)23-11-12-29-26-6-4-3-5-24(23)26/h3-12,15-19,28H,13-14H2,1-2H3/t18-,19+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	n/a
The Brigham and Women's Hospital, Inc.; Dept. of Health and Human Services, National Institutes of Health US Patent					Assay Description Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...				US Patent US9682983 (2017) BindingDB Entry DOI: 10.7270/Q28S4N3R
					More data for this Ligand-Target Pair