BDBM120814 US8716482, 17

SMILES: CS(=O)(=O)n1cc2CN(Cc2n1)[C@H]1C[C@H](N)C(N(Cc2cncc3cccnc23)C1)c1cc(F)ccc1F

InChI Key: InChIKey=AJVAWMWPWWAKLK-YHBFXGCJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM120814 (US8716482, 17) Show SMILES CS(=O)(=O)n1cc2CN(Cc2n1)[C@H]1C[C@H](N)C(N(Cc2cncc3cccnc23)C1)c1cc(F)ccc1F |r| Show InChI InChI=1S/C26H27F2N7O2S/c1-38(36,37)35-13-18-12-33(15-24(18)32-35)20-8-23(29)26(21-7-19(27)4-5-22(21)28)34(14-20)11-17-10-30-9-16-3-2-6-31-25(16)17/h2-7,9-10,13,20,23,26H,8,11-12,14-15,29H2,1H3/t20-,23-,26?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24.6	n/a	n/a	n/a	n/a	7.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...				US Patent US8716482 (2014) BindingDB Entry DOI: 10.7270/Q2G73CC0
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