BDBM120859 US8716478, D245::US9499570, D245

SMILES: CC(C)OCCOc1nc(Oc2cc3COB(O)c3c(C)c2)c(Cl)cc1C#N

InChI Key: InChIKey=XQZSDSGBZZUHKR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM120859 (US8716478, D245 | US9499570, D245) Show SMILES CC(C)OCCOc1nc(Oc2cc3COB(O)c3c(C)c2)c(Cl)cc1C#N Show InChI InChI=1S/C19H20BClN2O5/c1-11(2)25-4-5-26-18-13(9-22)8-16(21)19(23-18)28-15-6-12(3)17-14(7-15)10-27-20(17)24/h6-8,11,24H,4-5,10H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US9499570 (2016) BindingDB Entry DOI: 10.7270/Q2CZ363N
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM120859 (US8716478, D245 | US9499570, D245) Show SMILES CC(C)OCCOc1nc(Oc2cc3COB(O)c3c(C)c2)c(Cl)cc1C#N Show InChI InChI=1S/C19H20BClN2O5/c1-11(2)25-4-5-26-18-13(9-22)8-16(21)19(23-18)28-15-6-12(3)17-14(7-15)10-27-20(17)24/h6-8,11,24H,4-5,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	37
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US8716478 (2014) BindingDB Entry DOI: 10.7270/Q2Z60MQ7
					More data for this Ligand-Target Pair