BDBM12144 4-(N-(4-benzyloxyphenyl)aminocarbonyl-hydrazinocarbonyl)-benzenesulfonamide::N-({[4-(benzyloxy)phenyl]carbamoyl}amino)-4-sulfamoylbenzamide::urea analog 3h

SMILES: NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=GCIVACVOOQXDIE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM12144 (4-(N-(4-benzyloxyphenyl)aminocarbonyl-hydrazinocar...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H20N4O5S/c22-31(28,29)19-12-6-16(7-13-19)20(26)24-25-21(27)23-17-8-10-18(11-9-17)30-14-15-4-2-1-3-5-15/h1-13H,14H2,(H,24,26)(H2,22,28,29)(H2,23,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				J Med Chem 48: 2121-5 (2005) Article DOI: 10.1021/jm0494826 BindingDB Entry DOI: 10.7270/Q25X275C
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM12144 (4-(N-(4-benzyloxyphenyl)aminocarbonyl-hydrazinocar...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H20N4O5S/c22-31(28,29)19-12-6-16(7-13-19)20(26)24-25-21(27)23-17-8-10-18(11-9-17)30-14-15-4-2-1-3-5-15/h1-13H,14H2,(H,24,26)(H2,22,28,29)(H2,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				J Med Chem 48: 2121-5 (2005) Article DOI: 10.1021/jm0494826 BindingDB Entry DOI: 10.7270/Q25X275C
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM12144 (4-(N-(4-benzyloxyphenyl)aminocarbonyl-hydrazinocar...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H20N4O5S/c22-31(28,29)19-12-6-16(7-13-19)20(26)24-25-21(27)23-17-8-10-18(11-9-17)30-14-15-4-2-1-3-5-15/h1-13H,14H2,(H,24,26)(H2,22,28,29)(H2,23,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	-7.89	n/a	n/a	n/a	n/a	n/a	7.5	20
Universita degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				J Med Chem 48: 2121-5 (2005) Article DOI: 10.1021/jm0494826 BindingDB Entry DOI: 10.7270/Q25X275C
					More data for this Ligand-Target Pair