BDBM123814 4,5-dibromo-N'-(2-hydroxybenzylidene)-1H-pyrrole-2-carbohydrazide (4a)

SMILES: Oc1ccccc1C=NNC(=O)c1cc(Br)c(Br)[nH]1

InChI Key: InChIKey=VHMDLYVTLIKJOS-GIDUJCDVSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM123814 (4,5-dibromo-N'-(2-hydroxybenzylidene)-1H-pyrro...) Show SMILES Oc1ccccc1C=NNC(=O)c1cc(Br)c(Br)[nH]1 |w:8.9| Show InChI InChI=1S/C12H9Br2N3O2/c13-8-5-9(16-11(8)14)12(19)17-15-6-7-3-1-2-4-10(7)18/h1-6,16,18H,(H,17,19)/b15-6+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.90E+3	-7.16	n/a	n/a	n/a	n/a	n/a	7.4	37
University of KwaZulu-Natal					Assay Description The reaction mixtures (200 uL), containing recombinant human MAO-A or MAO-B (5 ug/mL) and the test compounds in potassium phosphate buffer (100 mM; p...				Chem Biol Drug Des 84: 593-602 (2014) Article DOI: 10.1111/cbdd.12352 BindingDB Entry DOI: 10.7270/Q2RB738C
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM123814 (4,5-dibromo-N'-(2-hydroxybenzylidene)-1H-pyrro...) Show SMILES Oc1ccccc1C=NNC(=O)c1cc(Br)c(Br)[nH]1 |w:8.9| Show InChI InChI=1S/C12H9Br2N3O2/c13-8-5-9(16-11(8)14)12(19)17-15-6-7-3-1-2-4-10(7)18/h1-6,16,18H,(H,17,19)/b15-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.78E+4	-6.27	n/a	n/a	n/a	n/a	n/a	7.4	37
University of KwaZulu-Natal					Assay Description The reaction mixtures (200 uL), containing recombinant human MAO-A or MAO-B (5 ug/mL) and the test compounds in potassium phosphate buffer (100 mM; p...				Chem Biol Drug Des 84: 593-602 (2014) Article DOI: 10.1111/cbdd.12352 BindingDB Entry DOI: 10.7270/Q2RB738C
					More data for this Ligand-Target Pair