BDBM123819 4,5-dibromo-N'-(3,4-dihydroxybenzylidene)-1Hpyrrole-2-carbohydrazide (4f)
SMILES: Oc1ccc(C=NNC(=O)c2cc(Br)c(Br)[nH]2)cc1O
InChI Key: InChIKey=APRISDUNRWLFIJ-PJQLUOCWSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM123819 (4,5-dibromo-N'-(3,4-dihydroxybenzylidene)-1Hpy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.73E+4 | -6.75 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of KwaZulu-Natal | Assay Description The reaction mixtures (200 uL), containing recombinant human MAO-A or MAO-B (5 ug/mL) and the test compounds in potassium phosphate buffer (100 mM; p... | Chem Biol Drug Des 84: 593-602 (2014) Article DOI: 10.1111/cbdd.12352 BindingDB Entry DOI: 10.7270/Q2RB738C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM123819 (4,5-dibromo-N'-(3,4-dihydroxybenzylidene)-1Hpy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.48E+4 | -6.17 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of KwaZulu-Natal | Assay Description The reaction mixtures (200 uL), containing recombinant human MAO-A or MAO-B (5 ug/mL) and the test compounds in potassium phosphate buffer (100 mM; p... | Chem Biol Drug Des 84: 593-602 (2014) Article DOI: 10.1111/cbdd.12352 BindingDB Entry DOI: 10.7270/Q2RB738C | |||||||||||
More data for this Ligand-Target Pair |