BDBM12534 (2S)-N-[2-(1H-azepin-1-yl)ethyl]-2-[(3S)-3-[(6-chloronaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]-N-(propan-2-yl)propanamide::P4 alanylamide pyrrolidin-2-one 45

SMILES: CC(C)N(CCN1C=CC=CC=C1)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

InChI Key: InChIKey=IWGAIPIVZUEJCP-LVXARBLLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM12534 ((2S)-N-[2-(1H-azepin-1-yl)ethyl]-2-[(3S)-3-[(6-chl...) Show SMILES CC(C)N(CCN1C=CC=CC=C1)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O |r,c:7,9,11| Show InChI InChI=1S/C28H33ClN4O4S/c1-20(2)32(17-16-31-13-6-4-5-7-14-31)27(34)21(3)33-15-12-26(28(33)35)30-38(36,37)25-11-9-22-18-24(29)10-8-23(22)19-25/h4-11,13-14,18-21,26,30H,12,15-17H2,1-3H3/t21-,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...				Bioorg Med Chem Lett 16: 5953-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.001 BindingDB Entry DOI: 10.7270/Q2CF9NB8
					More data for this Ligand-Target Pair