BDBM130234 US8815854, 30

SMILES: COc1ccc(cc1)-c1nc2ccc(nc2n1-c1ccc(cc1)C1(N)CCC1)-c1cccc(c1)N1CCOCC1

InChI Key: InChIKey=FHMAAJGJPPWXPV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM130234 (US8815854, 30) Show SMILES COc1ccc(cc1)-c1nc2ccc(nc2n1-c1ccc(cc1)C1(N)CCC1)-c1cccc(c1)N1CCOCC1 Show InChI InChI=1S/C33H33N5O2/c1-39-28-12-6-23(7-13-28)31-36-30-15-14-29(24-4-2-5-27(22-24)37-18-20-40-21-19-37)35-32(30)38(31)26-10-8-25(9-11-26)33(34)16-3-17-33/h2,4-15,22H,3,16-21,34H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.78	n/a	n/a	n/a	n/a	8.0	n/a
ArQule, Inc. US Patent					Assay Description AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...				US Patent US8815854 (2014) BindingDB Entry DOI: 10.7270/Q2J67FMR
					More data for this Ligand-Target Pair