BDBM132214 USRE45173, 153A::USRE45173, 189A

SMILES: Cc1c(cncc1C(F)(F)F)N1CCN(C1=O)c1ccc2ncsc2c1

InChI Key: InChIKey=PQDCNVLLXWMGJD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 132214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM132214 (USRE45173, 153A | USRE45173, 189A) Show SMILES Cc1c(cncc1C(F)(F)F)N1CCN(C1=O)c1ccc2ncsc2c1 Show InChI InChI=1S/C17H13F3N4OS/c1-10-12(17(18,19)20)7-21-8-14(10)24-5-4-23(16(24)25)11-2-3-13-15(6-11)26-9-22-13/h2-3,6-9H,4-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...				US Patent USRE45173 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FT2
					More data for this Ligand-Target Pair
Cytochrome P450 17A1 (Homo sapiens (Human))	BDBM132214 (USRE45173, 153A | USRE45173, 189A) Show SMILES Cc1c(cncc1C(F)(F)F)N1CCN(C1=O)c1ccc2ncsc2c1 Show InChI InChI=1S/C17H13F3N4OS/c1-10-12(17(18,19)20)7-21-8-14(10)24-5-4-23(16(24)25)11-2-3-13-15(6-11)26-9-22-13/h2-3,6-9H,4-5H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...				US Patent USRE45173 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FT2
					More data for this Ligand-Target Pair