BDBM136291 US8853212, DDP-4 Inhibitor 7

SMILES: CS(=O)(=O)n1cc2CN(Cc2n1)[C@H]1CSC([C@@H](N)C1)c1cc(F)cc(F)c1F

InChI Key: InChIKey=WOAQTPZMMMSKNP-JJNQEZICSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM136291 (US8853212, DDP-4 Inhibitor 7) Show SMILES CS(=O)(=O)n1cc2CN(Cc2n1)[C@H]1CSC([C@@H](N)C1)c1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C17H19F3N4O2S2/c1-28(25,26)24-6-9-5-23(7-15(9)22-24)11-4-14(21)17(27-8-11)12-2-10(18)3-13(19)16(12)20/h2-3,6,11,14,17H,4-5,7-8,21H2,1H3/t11-,14+,17?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.5	n/a
Merck Sharp & Dohme Corp US Patent					Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...				US Patent US8853212 (2014) BindingDB Entry DOI: 10.7270/Q2C53JK4
					More data for this Ligand-Target Pair