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SMILES: CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1ccnc(n1)C(F)(F)F

InChI Key: InChIKey=VYECYXGJHTUACZ-LQOMHORXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140218   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM140218
PNG
(US8906911, 27)
Show SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1ccnc(n1)C(F)(F)F |r|
Show InChI InChI=1S/C25H34F3N5O3/c1-35-20-14-36-8-5-19(20)30-16-9-15-3-2-6-24(15,11-16)23(34)33-13-17-10-18(33)12-32(17)21-4-7-29-22(31-21)25(26,27)28/h4,7,15-20,30H,2-3,5-6,8-14H2,1H3/t15-,16-,17+,18+,19+,20-,24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 444 -8.05 391n/an/an/an/a7.44



AbbVie Inc.

US Patent


Assay Description
Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...

US Patent US8906911 (2014)


BindingDB Entry DOI: 10.7270/Q2BV7FBV
More data for this
Ligand-Target Pair