BDBM140221 US8906911, 30

SMILES: CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1nc(cs1)C(F)(F)F

InChI Key: InChIKey=IRFFFXKBUHDQEI-KWYGVJCUSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM140221 (US8906911, 30) Show SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1nc(cs1)C(F)(F)F |r| Show InChI InChI=1S/C24H33F3N4O3S/c1-33-19-12-34-6-4-18(19)28-15-7-14-3-2-5-23(14,9-15)21(32)30-10-17-8-16(30)11-31(17)22-29-20(13-35-22)24(25,26)27/h13-19,28H,2-12H2,1H3/t14-,15-,16+,17+,18+,19-,23-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	831	-7.71	95.5	n/a	n/a	n/a	n/a	7.4	4
AbbVie Inc. US Patent					Assay Description Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...				US Patent US8906911 (2014) BindingDB Entry DOI: 10.7270/Q2BV7FBV
					More data for this Ligand-Target Pair