BDBM141361 US8916594, I-147

SMILES: CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)C1(C)CC(F)(F)C1

InChI Key: InChIKey=TVYXFTCMYLZZNJ-JOCQHMNTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Mus musculus (Mouse))	BDBM141361 (US8916594, I-147) Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)C1(C)CC(F)(F)C1 |r,wU:8.7,wD:11.14,(-9.71,.87,;-8.38,.1,;-8.38,-1.44,;-7.04,.87,;-7.81,2.21,;-6.27,2.21,;-5.71,.1,;-4.38,.87,;-3.04,.1,;-1.71,.87,;-.38,.1,;-.38,-1.44,;-1.71,-2.21,;-3.04,-1.44,;.96,-2.21,;2.29,-1.44,;3.76,-1.91,;4.66,-.67,;3.76,.58,;2.29,.1,;6.2,-.67,;5.43,.67,;7.29,-1.76,;8.38,-.67,;9.71,.1,;9.71,-1.44,;7.29,.42,)| Show InChI InChI=1S/C17H28F2N4O3S/c1-11(2)27(24,25)20-8-12-4-6-13(7-5-12)21-15-22-14(23-26-15)16(3)9-17(18,19)10-16/h11-13,20H,4-10H2,1-3H3,(H,21,22,23)/t12-,13-	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.610	n/a	n/a	n/a	n/a	7.4	25
Shionogi & Co., Ltd. US Patent					Assay Description cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...				US Patent US8916594 (2014) BindingDB Entry DOI: 10.7270/Q21G0K0S
					More data for this Ligand-Target Pair