BDBM141642 US8921389, 99::US9695170 99

SMILES: COC(=O)N(C)CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O

InChI Key: InChIKey=VIJYASAJVYYXJK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141642 (US8921389, 99 | US9695170 99) Show SMILES COC(=O)N(C)CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O Show InChI InChI=1S/C21H22N4O5/c1-24(21(29)30-2)11-9-22-19(27)17-18(26)15-8-10-25(20(28)16(15)12-23-17)13-14-6-4-3-5-7-14/h3-8,10,12,26H,9,11,13H2,1-2H3,(H,22,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9695170 (2017) BindingDB Entry DOI: 10.7270/Q2P55KN0
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141642 (US8921389, 99 | US9695170 99) Show SMILES COC(=O)N(C)CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O Show InChI InChI=1S/C21H22N4O5/c1-24(21(29)30-2)11-9-22-19(27)17-18(26)15-8-10-25(20(28)16(15)12-23-17)13-14-6-4-3-5-7-14/h3-8,10,12,26H,9,11,13H2,1-2H3,(H,22,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.4	n/a
Fibrogen, Inc. US Patent					Assay Description Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...				US Patent US8921389 (2014) BindingDB Entry DOI: 10.7270/Q20G3HV0
					More data for this Ligand-Target Pair