null

SMILES: Cc1cccc(NC(=O)N2CCC(CC2)C(NC2CCC(CC2)c2c[nH]c3cccnc23)C(N)=O)c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM141953 (US8921559, 48) Show SMILES Cc1cccc(NC(=O)N2CCC(CC2)C(NC2CCC(CC2)c2c[nH]c3cccnc23)C(N)=O)c1 |(10.52,-3.05,;9.19,-3.82,;9.19,-5.36,;7.85,-6.13,;6.52,-5.36,;6.52,-3.82,;5.19,-3.05,;3.85,-3.82,;3.85,-5.36,;2.52,-3.05,;2.52,-1.51,;1.18,-.74,;-.15,-1.51,;-.15,-3.05,;1.18,-3.82,;-1.48,-.74,;-2.82,-1.51,;-4.15,-.74,;-5.48,-1.51,;-6.82,-.74,;-6.82,.8,;-5.48,1.57,;-4.15,.8,;-8.15,1.57,;-9.62,1.1,;-10.52,2.34,;-9.62,3.59,;-9.94,5.1,;-8.79,6.13,;-7.33,5.65,;-7.01,4.14,;-8.15,3.11,;-1.48,.8,;-.15,1.57,;-2.82,1.57,;7.85,-3.05,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica NV US Patent					Assay Description MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...				US Patent US8921559 (2014) BindingDB Entry DOI: 10.7270/Q270804M
					More data for this Ligand-Target Pair